Agree with David, broomrape is a complete root parasitic weed which attach to tobacco roots and extracts nutrient and water leading to poor growth of tobacco plants. Generally high soil moisture and low soil temperature favors the broomrape outbreak.
Since hand weeding is only viable option- Central Tobacco Research Institute, Rajahmundry, India have developed a special spear which helps in complete killing of weeds.
http://www.ctri.org.in/for_controlDis...
Usually deep summer ploughing may helps in exposing weed seeds to sunlight and reducing weed population. Also make sure to remove the emerged weeds before flowering and burn them. Rotate the crop with sorghum, black gram etc., to reduce weed population (but avoid growing tomato, eggplant and okra in the same field since broomrape also attack this crops).
Broomrape parasitizing tomato
Broomrape (Orobanche cernua) seeds
Broomrape seeds
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